Gianluca SampietroProfessional title: Consultant Surgeon, Honorary Professor of Surgery

Date of primary qualification: 1996

Current institution: Department of Surgery 'Luigi Sacco' University Hospital, Italy

Title of presentation:
Surgical management of severe colorectal Crohn's disease

Learning objectives:
Indication and timing of surgical treatment of colorectal Crohn’s disease, with particular attention to preoperative medical therapy, intraoperative findings, operative strategy and postoperative results. Laparoscopic options will be emphasized and the place for IPAA specifically addressed.

Summary of clinical/research background

Responsible for a special unit designed to operate as a National Referral Center for the Surgical Treatment of IBD. The unit is part of a multidisciplinary network, together with gastroenterologists, pathologists, paediatricians, oncologists, rheumatologists and radiologists with the aim of providing high quality of care for IBD patients from the whole country. The outpatient’s clinic of Surgery and Stoma-therapy for IBD patients, organized jointly with a Consultant Gastroenterologist, has a volume of 500 patients a year; I’ve performed over 2000 surgical procedures in General, Oncologic, IBD, and Minimal Invasive Surgery. I’ve a special surgical interest in advanced colorectal and IBD laparoscopic surgery (more than 75% of abdominal procedure are performed laparoscopically). I’m specialist in enteral and parenteral nutrition for critical surgical patients, specialist in advanced wound dressings for surgical and trauma patients. I’m project leader and project partner in research projects in general and gastrointestinal surgery, and in basic science, clinical and surgical aspects of Inflammatory Bowel Disease. I’m author of original articles (Impact Factor 167,551), abstracts, book chapters, scientific CD-Roms and DVDs.

Relevant peer reviewed publications within last 5 years

  • Giovanni Maconi, Gianluca M Sampietro, Alessandra Sartani, Gabriele Bianchi Porro. Bowel ultrasound in Crohn’s disase. Surgical perspective. International journal of colorectal disase 2008;23(4):339-47 (impact factor 1.767)
  • Valentina Salucci, Monica Rimoldi, Chiara Penati, Gianluca M Sampietro, Marjan Maria Van Duist, Gianluca Matteoli, Simone Saibeni, Maurizio Vecchi, Sandro Ardizzone, Gabriele Bianchi Porro, and Maria Rescigno. Monocyte-derived dendritic cells from crohn patients show differential nod2/card15-dependent immune responses to bacteria. Inflammatory Dowel Disease 2008;14(6):812-8 (impact factor 4.975)
  • Gianluca M Sampietro, Fabio Corsi, Giovanni Maconi, Sandro Ardizone, Alice Frontali, Alberto Corona, Gabriele Bianchi Porro, And Diego Foschi. A prospective study of long-term results and prognostic factors after conservative surgery for small-bowel crohn’s disease. Clinical Gastroenterology and Hepatology 2009; 7:183-191 (impact factor 5.642)
  • Giovanni Maconi, Elisabetta Colombo, Gianluca M Sampietro, Francesca Lamboglia, Renata D’incà, Marco Daperno, Andrea Cassinotti, Giacomo C Sturniolo, Sandro Ardizzone, Piergiorgio Duca, Gabriele Bianchi Porro, Vito Annese. Card15 gene variants and risk of re-operation in crohn’s disease patients. American Journal of Gastroenterology 2009;104(10):2483-91 (impact factor 6.012)
  • Iliyan D Iliev, Ilaria Spadoni, Erika Mileti, Gianluca Matteoli, Angelica Sonzogni, Gianluca M Sampietro, Diego Foschi, Flavio Caprioli, Giuseppe Viale, And Maria Rescigno. Human intestinal epithelial cells promote the differentiation of tolerogenic dendritic cells. Gut 2009;58(11):1481-9 (impact factor 9,357)
  • Fabrizio Parente, Mirko Molteni, Barbara Marino, Alberto Colli, Sandro Ardizzone, Salvatore Greco, Gianluca Sampietro, Silvano Gallus. Bowel ultrasound and mucosal healing in ulcerative colitis. Digestive Diseases 2009;27(3):285-290 (impact factor 1.487)
  • Andrea Cassinotti, Satish Keshav, Sandro Ardizzone, Neil Mortensen, Gianluca Sampietro, Paolo Fociani, Piergiorgio Duca , Bruce George, Marco Lazzaroni, Gianpiero Manes, Brian Warren, Diego Foschi, Gianluca Vago, Gabriele Bianchi Porro, Simon Travis. IBD care in Europe: a comparative audit of the inpatient management of crohn's disease and ulcerative colitis using the national uk ibd audit tool. Journal of Crohn’s and Colitis 2009; 3(4):291-301 (impact factor 1.729)
  • Fabrizio Parente, Mirko Molteni, Barbara Marino, Alberto Colli, Sandro Ardizzone, Salvatore Greco, Gianluca Sampietro, Diego Foschi, Silvano Gallus. Are colonoscopy and bowel ultrasound useful to assess response to short-term therapy and predict disease outcome of moderate to severe forms of ulcerative colitis? A prospective study. American Journal of Gastroenterology 2010;105(5):1150-7 (impact factor 6.882)
  • Antonio Di Sabatino, Paolo Biancheri, Silvia Piconese, Manuela M. Rosado, Sandro Ardizzone, Laura Rovedatti, Cristina Ubezio, Alessandro Massari, Gianluca M. Sampietro, Diego Foschi, Gabriele Bianchi Porro, Mario P. Colombo, Rita Carsetti, Thomas T. Macdonald, Gino R. Corazza. Peripheral regulatory t cells and serum transforming growth factor beta: their relationship with the clinical response to infliximab in crohn’s disease. Inflammatory Bowel Diseases 2010; 16(11):1891-7 (impact factor 4.855)
  • Clerici, Mario. Cassinotti, Andrea. Onida, Francesco. Trabattoni, Daria. Annaloro, Claudio. Della Volpe, Aldo. Rainone, Veronica. Lissoni, Francesca. Duca, Piergiorgio. Sampietro, Gianluca. Fociani, Paolo. Vago, Gianluca. Foschi, Diego. Ardizzone, Sandro. Deliliers, giorgio lambertenghi. Porro, gabriele bianchi. Immunomodulatory effects of unselected haematopoietic stem cells autotransplantation in refractory Crohn's disease. Digestive & Liver disease 2011; 43(12):946-52 (impact factor 3.054)
  • Antonino Spinelli, Gianluca M Sampietro, Piero Bazzi, Matteo Sacchi, And Marco Montorsi. Surgical approach to ulcerative colitis: when is the best timing after medical treatment? Current Drug Targets. 2011; 12(10):1462-6. (impact factor 3.553)
  • Gianluca M Sampietro, Silvia Casiraghi, Diego Foschi. Perforating crohn’s disease: conservative and surgical treatment. Digestive Ddiseases 2013; 31:218-221. (impact factor 2.725)
  • Paolo Biancheri, Sylvia L.F. Pender, Francesca Ammoscato, Paolo Giuffrida, Gianluca Sampietro, Sandro Ardizzone, Amir Ghanbari, Renata Curciarello, Alessandra Pasini, Giovanni Monteleone, Gino R. Corazza, Thomas T. Macdonald, Antonio Di Sabatino. The role of interleukin 17 in Crohn’s disease intestinal fibrosis. Fibrogenesis & Tissue Repair 2013; in press

Information submitted for ESCP Belgrade 2013

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