AIN and Anal Cancer

Folder AIN and Anal Cancer

Documents

video Atypical colitis, proctology and anal neoplasia: Condylomata, HPV, and AIN

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Symposium - Andreas Salat (Austria) at ESCP Vienna 2019

video Atypical colitis, proctology and anal neoplasia: Personalised anal cancer management in 2020

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Symposium - Marianne G. Guren (Norway) at ESCP Vienna 2019

video Trainee Video Session: High resolution anuscopy (HRA)

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Educational session - Carlo Ratto (Italy) at ESCP Vienna 2019

video In vivo and in vitro efficacy of dual PI3K/mTOR inhibition in novel murine models of anal cancer

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ASCRS Visiting Fellow Free Paper - Brooks Rademacher at ESCP Berlin 2017

document Anal Intraepithelial Neoplasia and Anal Cancer (Chapter 27, European Manual of Medicine: Coloproctology Second Edition)

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Within the past few decades the incidence of anal cancer has increased worldwide, especially among the male homosexual population (men who have sex with men [MSM]), with an incidence up to 225 in 100,000. Human papillomavirus (HPV) infections are a main risk factor for the occurrence of anal cancer. The prevalence of anal HPV infection in human immunodeficiency virus (HIV)–negative MSM is 50–60 %, whereas the prevalence reaches almost 100 % in HIV-positive MSM. Anal intraepithelial neoplasia (AIN), which is associated with HPV, has been identified as a precursor lesion for anal cancer. Approximately 20 % of HIV-negative MSM are diagnosed with AIN, and high-grade epithelial neoplasia is already present in 5–10 %. The prevalence of high-grade AIN among HIV-positive MSM is considerably higher and can reach 50 %. In hypothetical models, screening examinations such as anal cytology and high-resolution anoscopy have been shown to be cost-effective and efficient in MSM. Based on these findings, regular anal screening tests should be recommended for at-risk patients. If anal cancer is diagnosed, positron emission tomography/computed tomography is recommended for staging. Radiochemotherapy is the standard treatment for most patients. Surgery is only advisable in patients with small tumors (<2 cm) of the anal margin or as a salvage procedure. Follow-up should be performed for 3 years and should include digital rectal examination and palpation of inguinal lymph nodes.

video Core Subject Update: AIN

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Educational session - Daniel Dindo at ESCP Milan 2016

video AIN and anal malignancy: AIN

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Symposium - Daniel Dindo at ESCP Dublin 2015

video AIN and anal malignancy: Pathological spectrum of anal neoplasia

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Symposium - Marianna Berho at ESCP Dublin 2015

video AIN and anal malignancy: Salvage surgery for anal cancer

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Symposium - Evgeny Rybakov at ESCP Dublin 2015

video Salvage surgery for anal squamous cell carcinoma: prognostic factors for recurrence and survival

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Oral Poster (Neoplasia) - Maziar Nikberg at ESCP Barcelona 2014

pdf Identification and exploration of novel therapeutic targets for anal cancer

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CSSANZ Travelling Fellow visiting paper - Maria-Pia Bernardi (Australia) at Tripartite Colorectal Meeting 2014

video Laser therapy for HPV perineal lesions

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Video Presentation - Guillermo Rosato (Argentina) at Tripartite Colorectal Meeting 2014

pdf Patterns of treatment failure for anal squamous cell cancer: thirty years experience in a single institution

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Short Paper - Maria-Pia Bernardi (Australia) at Tripartite Colorectal Meeting 2014

pdf Prognostic factors for survival in squamous cell anal carcinoma

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Short Paper - Zainul Abedin Kapacee (UK) at Tripartite Colorectal Meeting 2014

video Progress or regress? Natural history of anal dysplasia in HIV-infected patients

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Free paper - Laurent Siproudhis at ESCP Belgrade 2013

video How useful is magnetic resonance imaging in detecting anal cancer recurrence?

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Oral poster - Jan Lee at ESCP Belgrade 2013

video Proctology: Management of anal intra-epithelial neoplasia (AIN)

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Symposium - Per J. Nilsson at ESCP Vienna 2012

video Factors influencing recurrence after surgical treatment of ano-genital warts

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Oral poster - Massimiliano Mistrangelo at ESCP Sorrento 2010

ESCP Affiliates