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  • Anastomotic healing requires good blood flow, but the colonic vascular supply can be compromised by resection.
  • Collagen matrix in the submucosa is essential for structure and healing.
  • Intestinal microbiota probably influence leaks, but more research is required for us to understand this process.
  • The order in which resection and anastomosis is performed and its anatomical arrangement matter less than the need to ensure a good blood supply and the formation of a tension free anastomosis.
  • The decision between creating a hand sewn or stapled anastomosis should be individualised to each patient.
  • There are specific scenarios where stapled anastomosis is likely to be inappropriate.

The video below summarises a key learning point from this module, with a discussion about choice of handsewn versus stapled anastomoses:

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